Method for preparing guanidino acetic acid

A modified method for preparing guanidino acetic acid (GAA) involves reacting cyanamide with an excess molar amount of glycine in an aqueous reaction mixture, in the presence of a base. The method avoids high molar amounts of base or acid for pH control, and maintains the reaction selectivity and pr...

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Main Authors Ronneburg, Axel, Roth, Philipp, Stahl, Timo
Format Patent
LanguageEnglish
Published 24.10.2023
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Summary:A modified method for preparing guanidino acetic acid (GAA) involves reacting cyanamide with an excess molar amount of glycine in an aqueous reaction mixture, in the presence of a base. The method avoids high molar amounts of base or acid for pH control, and maintains the reaction selectivity and product yields.
Bibliography:Application Number: US202118043572