T cell receptors that bind to mixed lineage leukemia (MLL)-specific phosphopeptides and methods of use thereof
Provided are TCRs (e.g., TCRs that bind to MLL, e.g., TCRs that bind to an MLL phosphopeptide, e.g., TCRs that bind to an MLL phosphopeptide/MHC complex), cells and pharmaceutical compositions comprising these TCRs, nucleic acids encoding these TCRs, expression vectors and host cells for making thes...
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Main Authors | , , , , , , |
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Format | Patent |
Language | English |
Published |
08.08.2023
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Subjects | |
Online Access | Get full text |
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Summary: | Provided are TCRs (e.g., TCRs that bind to MLL, e.g., TCRs that bind to an MLL phosphopeptide, e.g., TCRs that bind to an MLL phosphopeptide/MHC complex), cells and pharmaceutical compositions comprising these TCRs, nucleic acids encoding these TCRs, expression vectors and host cells for making these TCRs, and methods of treating a subject using these TCRs. |
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Bibliography: | Application Number: US202016807742 |