Inhibitors of receptor interacting protein kinase I for the treatment of disease

Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.

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Bibliographic Details
Main Authors Reyna, Naphtali, Lewis, Richard T, Ray, William J, Ramaswamy, Suyambu Kesava Vijayan, Cross, Jason, Hamilton, Matthew, Alvarez, Fernando
Format Patent
LanguageEnglish
Published 08.08.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.
Bibliography:Application Number: US202017014184