Carboxamide-pyrimidine derivatives as SHP2 antagonists

The invention relates to carboxamide-pyrimidine derivatives of the general formula I,or a pharmaceutically acceptable salt thereof, and the use of the compounds of the present invention for the treatment of hyperproliferative diseases and disorders in mammals, especially humans, and pharmaceutical c...

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Bibliographic Details
Main Authors Musch, Doreen, Boivin, Roch, Mochalkin, Igor, Kumar, Deepak, Linde, Nina, Jorand-Lebrun, Catherine, Johnson, Theresa
Format Patent
LanguageEnglish
Published 11.07.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention relates to carboxamide-pyrimidine derivatives of the general formula I,or a pharmaceutically acceptable salt thereof, and the use of the compounds of the present invention for the treatment of hyperproliferative diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such compound.
Bibliography:Application Number: US202117245423