Tissue factor pathway inhibitor antibodies and uses thereof

The invention relates to antibodies, and antigen-binding fragments thereof, that specifically bind TFPI and inhibit an activity thereof. Such antibodies and fragments are useful for treating bleeding disorders and shortening clotting time.

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Bibliographic Details
Main Authors Jin, Macy, Apgar, James R, Hett, Sunita R, Pittman, Debra, Stahl, Mark, Holsti, Matthew, Jasuja, Reema, Benard, Susan, Carven, Gregory J, Juo, Zong Sean
Format Patent
LanguageEnglish
Published 25.04.2023
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention relates to antibodies, and antigen-binding fragments thereof, that specifically bind TFPI and inhibit an activity thereof. Such antibodies and fragments are useful for treating bleeding disorders and shortening clotting time.
Bibliography:Application Number: US202017102883