Substituted aminothiazoles as inhibitors of nucleases

Compounds represented by the structural formula (1) R1, R2, R3, R4, R5, R6 are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.

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Bibliographic Details
Main Authors Havel, Stepan, Nikulenkov, Fedor, Daniel, Lukas, Brezovsky, Jan, Carbain, Benoit, Sisakova, Alexandra, Damborsky, Jiri, Paruch, Kamil, Krejci, Lumir
Format Patent
LanguageEnglish
Published 21.02.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Compounds represented by the structural formula (1) R1, R2, R3, R4, R5, R6 are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.
Bibliography:Application Number: US201917047004