Designed ankyrin repeat domains with altered surface residues

The present invention relates to designed ankyrin repeat domains with altered surface residues, as well as to proteins comprising such a designed ankyrin repeat domain, nucleic acids encoding such domains or proteins, methods of preparing such proteins, pharmaceutical compositions comprising such pr...

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Bibliographic Details
Main Authors Venetz, Natalia, Levitsky, Victor, Binz, Hans Kaspar, Schilling, Johannes, Walser, Marcel, Forrer, Patrik
Format Patent
LanguageEnglish
Published 14.02.2023
Subjects
CHEMISTRY
COMBINATORIAL CHEMISTRY
HUMAN NECESSITIES
HYGIENE
LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to designed ankyrin repeat domains with altered surface residues, as well as to proteins comprising such a designed ankyrin repeat domain, nucleic acids encoding such domains or proteins, methods of preparing such proteins, pharmaceutical compositions comprising such proteins or nucleic acids, and the use of such proteins, nucleic acids or pharmaceutical compositions in the treatment of diseases.
Bibliography:Application Number: US202117400471