Inhibitors of TRPC6

The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts therefore, wherein R1 to R6, A, U, V, W, X, Y, and Z are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the tr...

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Main Authors Wu, Xinyuan, Brunette, Steven, Nicklin, Paul, Cui, Jianwen, Bouyssou, Thierry, Smith Keenan, Lana Louise, Lowe, Michael D, Turner, Michael Robert, Sarko, Christopher Ronald, Surprenant, Simon
Format Patent
LanguageEnglish
Published 01.11.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts therefore, wherein R1 to R6, A, U, V, W, X, Y, and Z are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
Bibliography:Application Number: US201916970129