ABC transporter peptide inhibitor XH-14C and application thereof

Provided are an ABC transporter peptide inhibitor XH-14C and an application thereof in the treatment of a tumor with multidrug resistance mediated by an ABC transporter. In the application, the peptide inhibitor XH-14C shown in SEQ ID NO: 1 is administered in combination with an ABC transporter subs...

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Bibliographic Details
Main Authors Feng, Luya, Luo, Xiaofang, Wang, Zongcheng, Qin, Zuodong
Format Patent
LanguageEnglish
Published 04.10.2022
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Provided are an ABC transporter peptide inhibitor XH-14C and an application thereof in the treatment of a tumor with multidrug resistance mediated by an ABC transporter. In the application, the peptide inhibitor XH-14C shown in SEQ ID NO: 1 is administered in combination with an ABC transporter substrate chemotherapeutic drug. This disclosure also provides a pharmaceutical composition for treating a tumor with multidrug resistance mediated by the ABC transporter, containing the peptide XH-14C shown in SEQ ID NO: 1 and an ABC transporter substrate chemotherapeutic drug.
Bibliography:Application Number: US202117324063