Antibody-containing aqueous formulation and use thereof

The present disclosure provides an antibody-containing aqueous formulation, comprising a therapeutically effective amount of an anti-interleukin-6 receptor antibody, a protein stabilizer, a surfactant, and a buffer. The buffer is an acetate buffer or a histidine buffer, and the antibody-containing a...

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Bibliographic Details
Main Authors Yang, Jheng-Gang, Liu, Jiung-Liang, Chang, Wen-Cheng
Format Patent
LanguageEnglish
Published 30.08.2022
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present disclosure provides an antibody-containing aqueous formulation, comprising a therapeutically effective amount of an anti-interleukin-6 receptor antibody, a protein stabilizer, a surfactant, and a buffer. The buffer is an acetate buffer or a histidine buffer, and the antibody-containing aqueous formulation has a pH ranging from 4.5 to 6.5.
Bibliography:Application Number: US201916371189