Cranberry-derived compositions for potentiating antibiotic efficacy against bacterial persistence

The present invention provides compositions derived from cranberry including xyloglucan and pectic oligosaccharides, and iridoid terpene glycosides. These compositions can be used in conjunction with antibiotics to synergistically kill bacterial persister cells and inhibit bacterial quiescent phenot...

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Bibliographic Details
Main Authors Sun, Jiadong, Deering, Robert, Rowley, David, Seeram, Navindra, Cohen, Paul
Format Patent
LanguageEnglish
Published 28.06.2022
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides compositions derived from cranberry including xyloglucan and pectic oligosaccharides, and iridoid terpene glycosides. These compositions can be used in conjunction with antibiotics to synergistically kill bacterial persister cells and inhibit bacterial quiescent phenotypes, thereby improving treatment outcomes in recurrent and other infections.
Bibliography:Application Number: US201816498359