Ultrasound frequency and microbubble size optimization in microbubble-enhanced ultrasound treatment

Various approaches for enhancing treatment of target tissue using a source of focused ultrasound while limiting damage to non-target tissue include selecting a frequency of ultrasound waves transmitted from the source of focused ultrasound for generating a focus in the target tissue; providing micro...

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Bibliographic Details
Main Authors Grinfeld, Javier, De Picciotto, Rafi, Levy, Yoav
Format Patent
LanguageEnglish
Published 14.06.2022
Subjects
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY
DIAGNOSIS
ELECTROTHERAPY
HUMAN NECESSITIES
HYGIENE
IDENTIFICATION
MAGNETOTHERAPY
MEDICAL OR VETERINARY SCIENCE
RADIATION THERAPY
SURGERY
ULTRASOUND THERAPY
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Summary:Various approaches for enhancing treatment of target tissue using a source of focused ultrasound while limiting damage to non-target tissue include selecting a frequency of ultrasound waves transmitted from the source of focused ultrasound for generating a focus in the target tissue; providing microbubbles having the first size distribution such that at least 50% of the microbubbles have a radius smaller than a critical radius corresponding to a resonance frequency matching the selected frequency of ultrasound waves; and applying the ultrasound waves at the selected frequency to treat the target tissue.
Bibliography:Application Number: US201816622004