Efficient crystallization process for preparing ultrapure Treprostinil and crystal prepared therefrom

There is provided a crystalline Form I of anhydrous Treprostinil and processes for the preparation thereof. The crystalline Form I of anhydrous Treprostnil is a stable crystalline form, which can provide steady physicochemical properties for pharmaceutical formulations, and is advantageous widely an...

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Main Authors Jheng, Jian-Bang, Hsu, Ming-Kun, Wei, Shih-Yi, Wei, Tzyh-Mann, Hsu, Min-Kuan
Format Patent
LanguageEnglish
Published 24.05.2022
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Abstract There is provided a crystalline Form I of anhydrous Treprostinil and processes for the preparation thereof. The crystalline Form I of anhydrous Treprostnil is a stable crystalline form, which can provide steady physicochemical properties for pharmaceutical formulations, and is advantageous widely and safety used in storage, shipment, and handling for commercially considerations.
AbstractList There is provided a crystalline Form I of anhydrous Treprostinil and processes for the preparation thereof. The crystalline Form I of anhydrous Treprostnil is a stable crystalline form, which can provide steady physicochemical properties for pharmaceutical formulations, and is advantageous widely and safety used in storage, shipment, and handling for commercially considerations.
Author Hsu, Ming-Kun
Hsu, Min-Kuan
Jheng, Jian-Bang
Wei, Tzyh-Mann
Wei, Shih-Yi
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Snippet There is provided a crystalline Form I of anhydrous Treprostinil and processes for the preparation thereof. The crystalline Form I of anhydrous Treprostnil is...
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CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
Title Efficient crystallization process for preparing ultrapure Treprostinil and crystal prepared therefrom
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