Efficient crystallization process for preparing ultrapure Treprostinil and crystal prepared therefrom

There is provided a crystalline Form I of anhydrous Treprostinil and processes for the preparation thereof. The crystalline Form I of anhydrous Treprostnil is a stable crystalline form, which can provide steady physicochemical properties for pharmaceutical formulations, and is advantageous widely an...

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Bibliographic Details
Main Authors Jheng, Jian-Bang, Hsu, Ming-Kun, Wei, Shih-Yi, Wei, Tzyh-Mann, Hsu, Min-Kuan
Format Patent
LanguageEnglish
Published 24.05.2022
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Summary:There is provided a crystalline Form I of anhydrous Treprostinil and processes for the preparation thereof. The crystalline Form I of anhydrous Treprostnil is a stable crystalline form, which can provide steady physicochemical properties for pharmaceutical formulations, and is advantageous widely and safety used in storage, shipment, and handling for commercially considerations.
Bibliography:Application Number: US201916720711