Chimeric antigen receptors containing a chlorotoxin domain
Chimeric transmembrane immunoreceptors (CAR) which include an extracellular domain that includes chlorotoxin or a related toxin, or a variant of chlorotoxin or a related toxin, that binds to human glioma or other human tumor cells, a transmembrane region, a costimulatory domain and an intracellular...
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Main Authors | , , , |
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Format | Patent |
Language | English |
Published |
25.01.2022
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Subjects | |
Online Access | Get full text |
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Summary: | Chimeric transmembrane immunoreceptors (CAR) which include an extracellular domain that includes chlorotoxin or a related toxin, or a variant of chlorotoxin or a related toxin, that binds to human glioma or other human tumor cells, a transmembrane region, a costimulatory domain and an intracellular signaling domain are described. |
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Bibliography: | Application Number: US201615767960 |