Kappa opioid receptor antagonists and products and methods related thereto
Compounds are provided that antagonize the kappa-opioid receptor (KOR) and products containing such compounds, as well as to methods of their use and synthesis. Such compounds have the structure of Formula (I), or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope or salt ther...
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Main Authors | , , , , , , , |
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Format | Patent |
Language | English |
Published |
21.09.2021
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Subjects | |
Online Access | Get full text |
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Summary: | Compounds are provided that antagonize the kappa-opioid receptor (KOR) and products containing such compounds, as well as to methods of their use and synthesis. Such compounds have the structure of Formula (I), or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope or salt thereof:wherein X, Y, R1, R2, R4, R5 R6, R7, R8 and R11 are as defined herein. |
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Bibliography: | Application Number: US202016846136 |