3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof

The present disclosure provides a compound of Formula (I′):or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, wherein R1, R2, Rx, X1, n, n1, and q are as defined herein, and methods of making and using same.

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Bibliographic Details
Main Authors Tichkule, Ritesh Bhanudasji, Visser, Michael Scott, Bonazzi, Simone, Fazal, Aleem, Beckwith, Rohan Eric John, Cernijenko, Artiom
Format Patent
LanguageEnglish
Published 06.07.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present disclosure provides a compound of Formula (I′):or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, wherein R1, R2, Rx, X1, n, n1, and q are as defined herein, and methods of making and using same.
Bibliography:Application Number: US202016835938