Macrocyclic indole derivatives

in which R1, R2, R3, R4, R5, R6, A and L are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical comp...

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Main Authors Johannes, Sarah Anna Liesa, Fitzgerald, Mark, Furst, Laura, Christ, Clara, Werbeck, Nicolas, Wei, Guo, Fernandez-Montalvan, Amaury, Moenning, Ursula, Kuhnke, Joachim, Lienau, Philip, Sack, Ulrike, Lemke, Chris, Serrano-Wu, Michael H, Scholz, Arne, Nasveschuk, Christopher, McCarren, Patrick R, Buchgraber, Philipp, Ferrara, Steven James, Klar, Ulrich, Eis, Knut, Thede, Kai, Lazarski, Kiel, Moewes, Manfred, McKinney, David
Format Patent
LanguageEnglish
Published 20.04.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:in which R1, R2, R3, R4, R5, R6, A and L are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.
Bibliography:Application Number: US201716301871