Nucleic acid sequences encoding transcription factors regulating alkaloid biosynthesis and their use in modifying plant metabolism

Plant metabolism and alkaloid levels can be regulated by transcription factors that regulate the nicotinic alkaloid biosynthetic pathway. In one embodiment, the disclosure provides a transcription factor that positively negatively regulates alkaloid biosynthesis, such as nicotine biosynthesis. In pa...

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Bibliographic Details
Main Authors Todd, Andrea T, Page, Jonathan
Format Patent
LanguageEnglish
Published 06.04.2021
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
CIGARETTES
CIGARS
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING ORCHEWING
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MOUTHPIECES FOR CIGARS OR CIGARETTES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SMOKERS' REQUISITES
SNUFF
SPIRITS
TOBACCO
TOBACCO SMOKE FILTERS
VINEGAR
WINE
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Summary:Plant metabolism and alkaloid levels can be regulated by transcription factors that regulate the nicotinic alkaloid biosynthetic pathway. In one embodiment, the disclosure provides a transcription factor that positively negatively regulates alkaloid biosynthesis, such as nicotine biosynthesis. In particular, the present disclosure provides methods for the inhibition of Nicotiana benthamiana auxin response factor 1 (NbTF1) to reduce alkaloid biosynthesis in plants.
Bibliography:Application Number: US201816041152