Bicyclic [4,6,0] hydroxamic acids as HDAC inhibitors

The present invention relates to inhibitors of zinc-dependent histone deacetylases (HDACs) useful in the treatment of diseases or disorders associated with HDAC6, having a Formulae I or Formula II:where R, L, X1, X2, X3, X4, X5, Y1, Y2, Y3, and Y4 are described herein.

Saved in:
Bibliographic Details
Main Authors Lancia, Jr., David R, Ng, Pui Yee, Rudnitskaya, Aleksandra, Zheng, Xiaozhang
Format Patent
LanguageEnglish
Published 22.12.2020
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:The present invention relates to inhibitors of zinc-dependent histone deacetylases (HDACs) useful in the treatment of diseases or disorders associated with HDAC6, having a Formulae I or Formula II:where R, L, X1, X2, X3, X4, X5, Y1, Y2, Y3, and Y4 are described herein.
Bibliography:Application Number: US201916522082