Double-stranded oligonucleotide molecules targeting p53 and methods of use thereof

The present application relates to nucleic acid compounds, compositions comprising same and methods of use thereof for treatment of various diseases, disorders and conditions. The compounds are preferably chemically synthesized and modified double-stranded nucleic acid molecules which down regulate...

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Bibliographic Details
Main Authors Kalinski, Hagar, Mett, Igor, Feinstein, Elena, Avkin-Nachum, Sharon
Format Patent
LanguageEnglish
Published 22.09.2020
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Summary:The present application relates to nucleic acid compounds, compositions comprising same and methods of use thereof for treatment of various diseases, disorders and conditions. The compounds are preferably chemically synthesized and modified double-stranded nucleic acid molecules which down regulate expression of a p53 gene.
Bibliography:Application Number: US201815942587