Therapeutic nanoparticles comprising a protonatable nitrogen therapeutic agent and methods of making and using same

The present disclosure generally relates to nanoparticles comprising a substantially hydrophobic acid, a basic therapeutic agent having a protonatable nitrogen, and a polymer. Other aspects include methods of making and using such nanoparticles.

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Bibliographic Details
Main Authors Figueiredo, Maria, Van Geen Hoven, Christina, Song, Yong-ho, Troiano, Greg, Dewitt, David, Peeke, Erick, Wang, Hong, Wright, James
Format Patent
LanguageEnglish
Published 10.03.2020
Subjects
HUMAN NECESSITIES
HYGIENE
MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES
MEDICAL OR VETERINARY SCIENCE
NANOTECHNOLOGY
PERFORMING OPERATIONS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES
TRANSPORTING
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Summary:The present disclosure generally relates to nanoparticles comprising a substantially hydrophobic acid, a basic therapeutic agent having a protonatable nitrogen, and a polymer. Other aspects include methods of making and using such nanoparticles.
Bibliography:Application Number: US201816124605