Method for influenza virus purification

A process for the purification of influenza virus or derivative thereof requires providing a source of influenza virus or derivative thereof, optionally subjecting the source to a pre-purification step, followed by subjecting the source to at least one chromatographic step on chromatographic materia...

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Bibliographic Details
Main Authors Peterka, Matjaz, Banjac, Marko, Roethl, Elisabeth, Kramberger, Petra, Muster, Thomas, Strancar, Ales
Format Patent
LanguageEnglish
Published 25.02.2020
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Summary:A process for the purification of influenza virus or derivative thereof requires providing a source of influenza virus or derivative thereof, optionally subjecting the source to a pre-purification step, followed by subjecting the source to at least one chromatographic step on chromatographic material selected from the group consisting of porous particles having mean pore sizes of at least 20 nm, perfusion particles, gel-in-a-shell particles, tentacle like particles, membrane adsorbers, and monoliths, and collecting fractions eluted from the chromatographic material that contain the influenza virus or derivative thereof, excluding sulfuric ester of cellulose or cross-linked polysaccharides.
Bibliography:Application Number: US201514791691