Mikto-arm star polymers for delivery of therapeutic agents
Mikto-arm star polymers were prepared comprising non-charged hydrophilic poly(ethylene oxide) arms and hydrophobic arms comprising a poly(propylene oxide) chain or phytol group. The polymer arms are covalently linked to a hydrophobic crosslinked polyester core formed by ring opening polymerization o...
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Format | Patent |
Language | English |
Published |
26.11.2019
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Abstract | Mikto-arm star polymers were prepared comprising non-charged hydrophilic poly(ethylene oxide) arms and hydrophobic arms comprising a poly(propylene oxide) chain or phytol group. The polymer arms are covalently linked to a hydrophobic crosslinked polyester core formed by ring opening polymerization of a bis-cyclic ester initiated by mono-nucleophilic polymer arm precursors. The mikto-arm star polymers show improved loading capacity for Coenzyme Q10 (CoQ10). |
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AbstractList | Mikto-arm star polymers were prepared comprising non-charged hydrophilic poly(ethylene oxide) arms and hydrophobic arms comprising a poly(propylene oxide) chain or phytol group. The polymer arms are covalently linked to a hydrophobic crosslinked polyester core formed by ring opening polymerization of a bis-cyclic ester initiated by mono-nucleophilic polymer arm precursors. The mikto-arm star polymers show improved loading capacity for Coenzyme Q10 (CoQ10). |
Author | Piunova, Victoria A Nor, Siti Mariam B. Mohd Malek, Emilia B. A Badri, Khairiah H |
Author_xml | – fullname: Nor, Siti Mariam B. Mohd – fullname: Malek, Emilia B. A – fullname: Badri, Khairiah H – fullname: Piunova, Victoria A |
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RelatedCompanies | International Business Machines Corporation NanoMalaysia Berhad |
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Title | Mikto-arm star polymers for delivery of therapeutic agents |
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