Covalently linked helicar-anti-helicar antibody conjugates and uses thereof

Herein is reported a conjugate comprising a helicar motif amino acid sequence containing compound and an antibody that specifically binds to the helicar motif amino acid sequence characterized by a covalent bond between the helicar motif amino acid sequence containing compound and an amino acid resi...

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Bibliographic Details
Main Authors Brinkmann, Ulrich, Moessner, Ekkehard, Dengl, Stefan, Tiefenthaler, Georg, Gaertner, Achim, Hoffmann, Eike, Georges, Guy
Format Patent
LanguageEnglish
Published 10.09.2019
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Herein is reported a conjugate comprising a helicar motif amino acid sequence containing compound and an antibody that specifically binds to the helicar motif amino acid sequence characterized by a covalent bond between the helicar motif amino acid sequence containing compound and an amino acid residue in the CDR2 of the anti-helicar antibody, whereby the CDR2 is determined according to Kabat.
Bibliography:Application Number: US201615200584