Methods, compositions, and systems for activation and expansion of cells

The disclosure provides for compositions, systems, and methods of cell expansion, stimulation and/or differentiation. The disclosure further provides for a mesh substrate and associated methods capable of stimulating cell expansion, for example, T cell or stem cell expansion. In another aspect, the...

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Bibliographic Details
Main Authors Bogdanowicz, Danielle, Bashour, Keenan T, Kam, Lance C, Lu, Helen H, De Leo, Sarah E, Chuang, Philip
Format Patent
LanguageEnglish
Published 28.05.2019
Subjects
BEER
BIOCHEMISTRY
BRAIDING
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
HUMAN NECESSITIES
HYGIENE
KNITTING
LACE-MAKING
LAUNDERING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
NON-WOVEN FABRICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TEXTILES
TREATMENT OF TEXTILES OR THE LIKE
TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS,FABRICS, FEATHERS, OR FIBROUS GOODS MADE FROM SUCH MATERIALS
TRIMMINGS
VINEGAR
WINE
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Summary:The disclosure provides for compositions, systems, and methods of cell expansion, stimulation and/or differentiation. The disclosure further provides for a mesh substrate and associated methods capable of stimulating cell expansion, for example, T cell or stem cell expansion. In another aspect, the disclosure provides for an electrospun mesh substrate and methods of using thereof comprising a silicone rubber composition, for example, polydimethylsiloxane, PLC, or combinations thereof.
Bibliography:Application Number: US201515302475