WDR5 inhibitors and modulators

Described are compounds that disrupt the WDR5-MLL1 protein-protein interaction, pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating disorders and conditions in a subject.

Saved in:
Bibliographic Details
Main Authors Wang, Feng, Jeon, KyuOk, Gogliotti, Rocco D, Tansey, William P, Fesik, Stephen W, Stauffer, Shaun R, Olejniczak, Edward T, Phan, Jason
Format Patent
LanguageEnglish
Published 25.12.2018
Subjects
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:Described are compounds that disrupt the WDR5-MLL1 protein-protein interaction, pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating disorders and conditions in a subject.
Bibliography:Application Number: US201715703289