Complexes of abiraterone acetate, process for the preparation thereof and pharmaceutical compositions containing them

The present disclosure relates to pharmaceutically acceptable complex formulae comprising complexes of Abiraterone acetate and pharmaceutically acceptable excipients, process for the preparation thereof and pharmaceutical compositions containing them. The complex formulae of the present disclosure h...

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Main Authors Filipcsei, Genovéva, Solymosi, Tamás, Angi, Réka, Jordán, Tamás, Basa-Dénes, Orsolya, Glavinas, Hristos, Ötvös, Zsolt
Format Patent
LanguageEnglish
Published 20.11.2018
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present disclosure relates to pharmaceutically acceptable complex formulae comprising complexes of Abiraterone acetate and pharmaceutically acceptable excipients, process for the preparation thereof and pharmaceutical compositions containing them. The complex formulae of the present disclosure have improved physicochemical properties which results in reduced food effect which allows significant dose reduction and the abandoning of the requirement of taking the drug on an empty stomach.
Bibliography:Application Number: US201715456988