Microbiological process

A process for the microbial synthesis of migalastat, specifically a process for the production of migalastat comprising culturing a microorganism under conditions such that at least one imino sugar is produced and detecting and/or isolating an imino sugar produced by said microorganism, and the micr...

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Bibliographic Details
Main Authors Collis, Andrew John, Dann, Alison Sarah, Ready, Sarah Jane, Alvarez-Ruiz, Emilio, Fosberry, Andrew Peter, Vazquez Muniz, Maria Jesus
Format Patent
LanguageEnglish
Published 18.09.2018
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Summary:A process for the microbial synthesis of migalastat, specifically a process for the production of migalastat comprising culturing a microorganism under conditions such that at least one imino sugar is produced and detecting and/or isolating an imino sugar produced by said microorganism, and the microorganisms used in this process. The invention also comprises migalastat produced according to the above method and pharmaceutical compositions and uses thereof.
Bibliography:Application Number: US201515118924