Pyrrolidine amide compounds as histone demethylase inhibitors
The present invention relates to compounds useful as inhibitors of one or more histone demethylases, such as KDM5. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various dis...
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| Main Authors | , , , , , , , , |
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| Format | Patent |
| Language | English |
| Published |
17.07.2018
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention relates to compounds useful as inhibitors of one or more histone demethylases, such as KDM5. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders. |
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| AbstractList | The present invention relates to compounds useful as inhibitors of one or more histone demethylases, such as KDM5. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders. |
| Author | Lai, Kwong Wah Labadie, Sharada Kiefer, James Gehling, Victor S Harmange, Jean-Christophe Ortwine, Daniel Dragovich, Peter Liang, Jun Zhang, Birong |
| Author_xml | – fullname: Labadie, Sharada – fullname: Liang, Jun – fullname: Dragovich, Peter – fullname: Kiefer, James – fullname: Harmange, Jean-Christophe – fullname: Zhang, Birong – fullname: Lai, Kwong Wah – fullname: Ortwine, Daniel – fullname: Gehling, Victor S |
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| Notes | Application Number: US201715482584 |
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| Snippet | The present invention relates to compounds useful as inhibitors of one or more histone demethylases, such as KDM5. The invention also provides pharmaceutically... |
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| Title | Pyrrolidine amide compounds as histone demethylase inhibitors |
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