Pyrrolidine amide compounds as histone demethylase inhibitors

The present invention relates to compounds useful as inhibitors of one or more histone demethylases, such as KDM5. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various dis...

Full description

Saved in:
Bibliographic Details
Main Authors Labadie, Sharada, Liang, Jun, Dragovich, Peter, Kiefer, James, Harmange, Jean-Christophe, Zhang, Birong, Lai, Kwong Wah, Ortwine, Daniel, Gehling, Victor S
Format Patent
LanguageEnglish
Published 17.07.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:The present invention relates to compounds useful as inhibitors of one or more histone demethylases, such as KDM5. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders.
Bibliography:Application Number: US201715482584