BENZIMIDAZOLE DERIVATIVES USEFUL IN TREATMENT OF VANILLOID RECEPTOR TRPV1 RELATED DISORDERS

• Main Authors: BROWN WILLIAM, JOHNSTONE SHAWN, LABRECQUE, DENIS
• Format: Patent
• Language: English; Russian; Ukrainian
• Published: 12.12.2011
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The claimed invention provides benzimidazole derivatives antagonists of VR1, processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds of Formula I may be used in the treatment of osteoarthritis, chronic tendinitis, pelvic pain and periphera...