Method of preparing and purifying an intermediate of methyl auristatin e
A method for preparing and purifying a monomethyl auristantin E intermediate. The method has the advantages of few steps, simple operation, cheap and easily available raw materials, high safety, a simple purification method and extremely high purity of a purified product, and the yield of the method...
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Main Authors | , , , , , , , , |
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Format | Patent |
Language | Chinese English |
Published |
21.05.2024
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Subjects | |
Online Access | Get full text |
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Summary: | A method for preparing and purifying a monomethyl auristantin E intermediate. The method has the advantages of few steps, simple operation, cheap and easily available raw materials, high safety, a simple purification method and extremely high purity of a purified product, and the yield of the method can be as high as 95%, which not only improves the safety of the production process, but also significantly improves the yield of the product, and reduces the subsequent production cost. Therefore, the method is suitable for industrial popularization. |
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Bibliography: | Application Number: TW202312112989 |