Bispecific antibodies specific for a costimulatory tnf receptor

The invention relates to novel bispecific antigen binding molecules, comprising (a) at least one moiety capable of specific binding to a target cell antigen, (b) at least one moiety capable of specific binding to a costimulatory TNF receptor family member, and (c) a Fc domain composed of a first and...

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Main Authors HOSSE, RALF, LEVITSKI, VIKTOR, KLEIN, CHRISTIAN, BRUENKER, PETER, CLAUS, CHRISTINA, UMANA, PABLO, AMANN, MARIA, GRAU-RICHARDS, SANDRA, FERRARA KOLLER, CLAUDIA
Format Patent
LanguageChinese
English
Published 11.08.2023
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to novel bispecific antigen binding molecules, comprising (a) at least one moiety capable of specific binding to a target cell antigen, (b) at least one moiety capable of specific binding to a costimulatory TNF receptor family member, and (c) a Fc domain composed of a first and a second subunit capable of stable association, and to methods of producing these molecules and to methods of using the same.
Bibliography:Application Number: TW202211103890