Cell purification module, cell purification system and operation method thereof

• Main Authors: YU, WEI-LIN, LIN, MENG-HSUEH, HUANG, CHIHIEH, HSU, LIH-TAO, WU, CHENG-YI, PENG, SHEN-HUA, HUANG, HUI-TING, KUO, JENG-LIANG
• Format: Patent
• Language: Chinese; English
• Published: 11.07.2023
• Subjects: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

A cell purification module is used to purify a plurality of cells from a fluid sample. The cell purification module includes a hollow column, a plurality of hollow fiber membranes, at least one first magnetic component, a fluid sample inlet end and a fluid sample outlet end. The hollow column has a first opening, a second opening opposite to the first opening and an accommodating space connecting the first opening and the second opening. The hollow fiber membranes are disposed in the accommodating space and each hollow fiber membrane has a plurality of pores. The first magnetic component is arranged around the hollow column. The fluid sample inlet end is located at one end of the hollow column. The fluid sample outlet end is located at the other end of the hollow column. The hollow column has an axial direction extending along an axis of the hollow column, a radial direction along a cross-sectional radius direction of the hollow column and perpendicular to the axis direction of the hollow column, and a circum