Compounds and uses thereof for the modulation of hemoglobin

Provide herein are compounds containing an aldehyde group and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or...

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Main Authors XU, QING, GWALTNEY, STEPHEN L, YEE, CALVIN W, METCALF, BRIAN W, CHUANG, CHIH YUAN, HARRIS, JASON R, LI, ZHE
Format Patent
LanguageChinese
English
Published 11.03.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provide herein are compounds containing an aldehyde group and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.
Bibliography:Application Number: TW20198127539