Direct selection of cells expressing high levels of heteromeric proteins using glutamine synthetase intragenic complementation vectors
This invention relates to the general field of recombinant expression of polypeptides in animal cell culture. More specifically, the invention concerns improved selection of cells transfected with recombinantly engineered vectors designed to express polypeptides, in particular heteromultimeric polyp...
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Main Authors | , , , , , |
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Format | Patent |
Language | Chinese English |
Published |
11.03.2022
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Subjects | |
Online Access | Get full text |
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Abstract | This invention relates to the general field of recombinant expression of polypeptides in animal cell culture. More specifically, the invention concerns improved selection of cells transfected with recombinantly engineered vectors designed to express polypeptides, in particular heteromultimeric polypeptides. |
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AbstractList | This invention relates to the general field of recombinant expression of polypeptides in animal cell culture. More specifically, the invention concerns improved selection of cells transfected with recombinantly engineered vectors designed to express polypeptides, in particular heteromultimeric polypeptides. |
Author | MCGREW, JEFFREY T MUNRO, TRENT PHILLIP AGRAWAL, NEERAJ JAGDISH KET, RANDAL ROBERT FOMINA YADLIN, DINA A DARIS, KRISTINE MARIE |
Author_xml | – fullname: MUNRO, TRENT PHILLIP – fullname: MCGREW, JEFFREY T – fullname: KET, RANDAL ROBERT – fullname: AGRAWAL, NEERAJ JAGDISH – fullname: DARIS, KRISTINE MARIE – fullname: FOMINA YADLIN, DINA A |
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Snippet | This invention relates to the general field of recombinant expression of polypeptides in animal cell culture. More specifically, the invention concerns... |
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SubjectTerms | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
Title | Direct selection of cells expressing high levels of heteromeric proteins using glutamine synthetase intragenic complementation vectors |
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