A novel il33 form, mutated forms of il33, antibodies, assays and methods of using the same

The present invention provides isolated IL-33 proteins, active fragments thereof and antibodies, antigen binding fragments thereof, against IL-33 proteins. Also provided are methods of modulating cytokine activity, e.g., for the purpose of treating immune and inflammatory disorders.

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Bibliographic Details
Main Authors STRAIN, MARTIN D, CARMEN, SARA, OVERED-SAYER, CATHERINE L, SCOTT, IAN C, MUSTELIN, TOMAS M, KEMP, BENJAMIN P, REES, DAVID G, LOWE, DAVID C, VOUSDEN, KATHERINE A, HOUSLAY, KIRSTY, COHEN, EMMA S, ENGLAND, ELIZABETH H, SLEEMAN, MATTHEW, BUTLER, ROBIN
Format Patent
LanguageChinese
English
Published 21.03.2021
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention provides isolated IL-33 proteins, active fragments thereof and antibodies, antigen binding fragments thereof, against IL-33 proteins. Also provided are methods of modulating cytokine activity, e.g., for the purpose of treating immune and inflammatory disorders.
Bibliography:Application Number: TW20165110432