Drug-device unit containing quinagolide

The present invention is based on the identification of a cohort of polyurethane block copolymers that are particularly suited for use in pharmaceutical polymeric drug-device units and which offer improved control of drug release. In particular, there is provided a polymeric drug-device unit compris...

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Bibliographic Details
Main Authors ROSS, ALISTAIR, YOUNG, CLAIRE, ARCE SAEZ, JOAN CARLES, COCHRANE, ROBERT, RABANI, GOUHER, MCDONALD, PAUL, HALLIDAY, JANET, PETRI, AXEL NICLAS, CARR, DENIS, QADIR, MOHAMMAD
Format Patent
LanguageChinese
English
Published 21.02.2020
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention is based on the identification of a cohort of polyurethane block copolymers that are particularly suited for use in pharmaceutical polymeric drug-device units and which offer improved control of drug release. In particular, there is provided a polymeric drug-device unit comprising a polyurethane block copolymer obtainable by reacting together a poly(alkylene oxide); a difunctional compound; a difunctional isocyanate; and optionally a block copolymer comprising poly(alkylene oxide) blocks; and quinagolide as a pharmaceutically active agent. The drug-device units may find application in the treatment and/or prevention of endometriosis.
Bibliography:Application Number: TW20154136694