Aromatic compound and pharmaceutical composition c

• Main Authors: KOJIMA, YUTAKA, SATOU, HIDEAKI, TAKASU, HIDEKI, KAN, KEIZO, OHI, NAOTO, NAKAGAWA, TAKASHI, MIYAJIMA, KEISUKE, YANAGIHARA, YASUO, YASUMURA, KOICHI, ITO, NOBUAKI, SUGIYAMA, KAZUHISA, FUKUSHIMA, TAE, KIYONO, KUNIHIKO, SUMIDA, TAKUMI, SHITSUTA, TAKUYA, TANAKA, MICHINORI, OKUNO, MITSUHIRO, WATANABE, KENJI, NAGAO, HITOSHI, TSUTSUI, HIRONORI, AKAMATSU, SEIJI, YAMADA, SATOSHI, TAKEMURA, NORIAKI, MATSUMURA, SHUJI, TAI, KUNINORI, KODAMA, TAKESHI, SUZUKI, TAKASHI, SAKAMOTO, MAKOTO
• Format: Patent
• Language: Chinese; English
• Published: 11.12.2011
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The compound of the present invention is represented by the following general formula (1): [wherein X1 represents a nitrogen atom or a group -CH ; R1 represents a group -Z-R6, wherein Z represents a group -CO-, a group -CH(OH)-, or the like, and R6 represents a 5- to 15-membered monocyclic, dicyclic, or tricyclic, saturated or unsaturated heterocyclic group having 1 to 4 nitrogen atoms, oxygen atoms, or sulfur atoms; R2 represents a hydrogen atom, a halogen atom or a lower alkylene group; Y represents a group -O-, a group -CO-, a group -CH(OH)-, a lower alkylene group, or the like; and A represents a group or the like, wherein R3 represents a hydrogen atom, a lower alkoxy group, or the like, p represents 1 or 2, and R4 represents an imidazolyl lower alkyl group or the like.