6,7-unsaturated-7-carbamoylmorphinan derivatives
A novel compound which is useful as an agent for treating and/or preventing emesis, vomiting and/or constipation. A compound represented by the formula (I): wherein R 1 and R 2 are each independently hydrogen, optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally subst...
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Main Authors | , , , , , |
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Format | Patent |
Language | Chinese English |
Published |
21.06.2009
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Subjects | |
Online Access | Get full text |
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Summary: | A novel compound which is useful as an agent for treating and/or preventing emesis, vomiting and/or constipation. A compound represented by the formula (I):
wherein R 1 and R 2 are each independently hydrogen, optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted cycloalkyl, optionally substituted aryl etc., R 3 is hydrogen, hydroxy, optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkynyl, optionally substituted lower alkoxy etc., R 4 is hydrogen or lower alkyl, R 5 is hydrogen, lower alkyl, cycloalkyl lower alkyl or lower alkenyl,
or a pharmaceutically acceptably salt, or a solvate thereof is provided. |
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Bibliography: | Application Number: TW200695118443 |