Enzymatic hydroxylation process for the preparation of HMG-COA reductase inhibitors and intermediates thereof

An enzymatic hydroxylation process for the preparation of compounds useful as HMG-COA reductase inhibitors and/or as intermediates in the preparation of HMG-COA reductase inhibitors uses a microorganism or an enzyme derived from, or having the structure of an enzyme derived from, said microorganism,...

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Bibliographic Details
Main Authors SZARKA, LASZLO J, CINO, PAUL M, DAVIS, BRIAN L
Format Patent
LanguageEnglish
Published 07.06.2001
Edition7
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES USING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:An enzymatic hydroxylation process for the preparation of compounds useful as HMG-COA reductase inhibitors and/or as intermediates in the preparation of HMG-COA reductase inhibitors uses a microorganism or an enzyme derived from, or having the structure of an enzyme derived from, said microorganism, which is capable of catalyzing the hydroxylation process.
Bibliography:Application Number: TW199483109094