Pyridazinone derivatives

Pyridazinone derivatives represented by the formula (I) and antiplatelet agents containing them: formula I, [wherein R is a hydrogen atom or a C1-C4 alkyl group, X is a hydrogen atom, a chlorine atom or a bromine atom, Ar is a pyridyl group or a phenyl group substituted with OR1 (wherein R1 is a hyd...

Full description

Saved in:
Bibliographic Details
Main Authors MATSUMOTO, TAKASHI, TSURUZOE, NOBUTOMO, NAKABEPPU, HITOSHI, MATSUMOTO, HIROO, TANIKAWA, KEIZO
Format Patent
LanguageEnglish
Published 01.02.2001
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:Pyridazinone derivatives represented by the formula (I) and antiplatelet agents containing them: formula I, [wherein R is a hydrogen atom or a C1-C4 alkyl group, X is a hydrogen atom, a chlorine atom or a bromine atom, Ar is a pyridyl group or a phenyl group substituted with OR1 (wherein R1 is a hydrogen atom or a C1-C4 alkyl group) and A {wherein A is a hydrogen atom, a halogen atom, a C1-C4 alkyl group or OR2 (wherein R2 is a hydrogen atom or a C1-C4 alkyl group)}, Y is C1-C8 alkylene wherein one carbon atom on the straight chain is substituted with one OR1 group (wherein R1 is the same as defined above), and Z1 and Z2 are independently a hydrogen atom, a halogen atom, a C1-C4 alkyl group or a OR1 group (wherein R1 is the same as defined above)]. These compounds have strong antiplatelet effects, are excellently safe, and can be used as active ingredients of prophylactic and therapeutic drugs for various thrombotic diseases.
Bibliography:Application Number: TW199584100797