4-anilino-quinazoline derivatives for use in treating, inhibiting the growth of or eradicating neoplasms, preparation method and pharmaceutical composition thereof

• Main Authors: FLOYD, MIDDLETON B. JR, KITCHEN, DOUGLAS B, WISSNER, ALLAN, JOHNSON, BERNARD D
• Format: Patent
• Language: English
• Published: 21.08.2000
• Edition: 7
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

A compound of the formula I wherein: X is phenyl substituted with one or two substituents selected from the group consisting of halogen, alkyl of 1-6 carbon atoms, hydroxy, trifluoromethyl; R and R1 are hydrogen; R2 is hydrogen; Y is a radical selected from the group consisting of cyclopentenyl, (fo...