4-anilino-quinazoline derivatives for use in treating, inhibiting the growth of or eradicating neoplasms, preparation method and pharmaceutical composition thereof

A compound of the formula I wherein: X is phenyl substituted with one or two substituents selected from the group consisting of halogen, alkyl of 1-6 carbon atoms, hydroxy, trifluoromethyl; R and R1 are hydrogen; R2 is hydrogen; Y is a radical selected from the group consisting of cyclopentenyl, (fo...

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Bibliographic Details
Main Authors FLOYD, MIDDLETON B. JR, KITCHEN, DOUGLAS B, WISSNER, ALLAN, JOHNSON, BERNARD D
Format Patent
LanguageEnglish
Published 21.08.2000
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A compound of the formula I wherein: X is phenyl substituted with one or two substituents selected from the group consisting of halogen, alkyl of 1-6 carbon atoms, hydroxy, trifluoromethyl; R and R1 are hydrogen; R2 is hydrogen; Y is a radical selected from the group consisting of cyclopentenyl, (formula), (formula), and (formula) R3 is independently hydrogen, alkyl of 1-6 carbon atoms, carboxy, carboalkoxy of 1-6 carbon atoms, or phenyl; or a pharmaceutically acceptable salt thereof, with the proviso that each R3 of Y may be the same or different.
Bibliography:Application Number: TW199786101229