Watersoluble azole antifungals

• Main Authors: BACKX, LEO JACOBUS JOZEF, HEERES, JAN, MESENS, JEAN L, VAN DER EYCKEN, LUC ALFONS LEO, ODDS, FRANK CHRISTOPHER
• Format: Patent
• Language: Chinese; English
• Published: 11.12.1999
• Subjects: ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM; AGRICULTURE; ANIMAL HUSBANDRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; CHEMISTRY; FISHING; FORESTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HUNTING; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; TRAPPING

A compound of formula (I), (I), an acid or base addition salt thereof or a stereochemically isomeric form thereof, wherein A and B taken together form -N=CH-, -CH=N-, -CH2=CH-, -C(=O)-CH2-, -CH2-C(=O); D is a radical of formula, (D1)(D2)(D3), L is a radical of formula, (L1)(L2), Alk is a C1-4-alkanediyl radical; R1 is halo; R2 is hydrogen or halo; R3 is hydrogen, C1-6-alkyl, phenyl or halophenyl; R4 is hydrogen, C1-6-alkyl, phenyl or halophenyl; R5 is hydrogen r C1-6-alkyl; R6 is hydrogen, C1-6-alkyl, C1-6-alkyloxycarbonyl, or R5 and R6 taken together with the nitrogen atom to which they are attached form a heterocyclic ring. Active intermediates, compositions and methods of preparing compounds, compositions are described.