Novel benzodiazepine derivatives

A novel benzodiazepine derivatives represented by the formula (I): R1 is a single bond, -CH2-, -CH2O-, -OCH2-, SCH2, or a group of the formula: R2 is a lower alkyl, -COOR5, -CONH(CH2)nCOOR5, SO2NHCOR5, or an optionally substituted heterocyclic group; R5 is a hydrogen atom, lower alkyl or benzyl; and...

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Bibliographic Details
Main Authors SENO KAORU, KAMADA SUSUMU, HAGA NOBUHIRO, ISHIWARA YASUNOBU, HAGISHITA SANJI
Format Patent
LanguageChinese
English
Published 21.06.1998
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Summary:A novel benzodiazepine derivatives represented by the formula (I): R1 is a single bond, -CH2-, -CH2O-, -OCH2-, SCH2, or a group of the formula: R2 is a lower alkyl, -COOR5, -CONH(CH2)nCOOR5, SO2NHCOR5, or an optionally substituted heterocyclic group; R5 is a hydrogen atom, lower alkyl or benzyl; and n is an integer of 1 to 5; R3 is a single bond, -CO- or -CONH-, and R4 is an optionally substituted lower alkyl, optionally substituted aryl or lower lkoxycarbonyl group, or a pharmaceutically acceptable salt.
Bibliography:Application Number: TW199483112110