Nucleic acids for inhibiting expression of AGT in a cell
The invention relates to double-stranded nucleic acid molecules that interfere with or inhibit angiotensinogen (AGT) gene expression. It further relates to therapeutic uses of such inhibition such as for the treatment of AGT-mediated diseases, disorders or syndromes, such as hypertension, pregnancy-...
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Main Authors | , , , |
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Format | Patent |
Language | Chinese English |
Published |
16.03.2024
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Subjects | |
Online Access | Get full text |
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Summary: | The invention relates to double-stranded nucleic acid molecules that interfere with or inhibit angiotensinogen (AGT) gene expression. It further relates to therapeutic uses of such inhibition such as for the treatment of AGT-mediated diseases, disorders or syndromes, such as hypertension, pregnancy-associated hypertension, borderline hypertension, diabetic hypertension, resistant hypertension, primary hypertension, secondary hypertension, chronic heart failure, stroke, non-alcoholic steatohepatitis (NASH), and/or non-alcoholic fatty liver disease (NAFLD). |
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Bibliography: | Application Number: TW202312126345 |