Nectin-4 binding agents

The invention relates to antibodies and antibody fragment that bind to Nectin-4 polypeptides. The invention also relates to antibody-drug conjugates that comprise the antibodies or antibody fragments, and to methods of making the conjugates, pharmaceutical compositions, and method of using them to d...

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Bibliographic Details
Main Authors KRAIEM, MANEL, CHANTEUX, STEPHANIE, GAUTHIER, LAURENT, ROSSI, BENJAMIN
Format Patent
LanguageChinese
English
Published 16.03.2024
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to antibodies and antibody fragment that bind to Nectin-4 polypeptides. The invention also relates to antibody-drug conjugates that comprise the antibodies or antibody fragments, and to methods of making the conjugates, pharmaceutical compositions, and method of using them to diagnose, treat or prevent diseases, e.g. cancer characterized by Nectin-4 expressing tumor cells.
Bibliography:Application Number: TW202312119460