Methods and systems for treating disease using an ATR/CHK1 signaling pathway inhibitor

Provided herein are methods and systems for determining and/or validating response to a checkpoint kinase 1 (Chk1) inhibitor, a Wee1 inhibitor, an ATR inhibitor, or a combination thereof, and methods of administering a Chk1 inhibitor, a Wee1 inhibitor, an ATR inhibitor, or a combination thereof to a...

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Bibliographic Details
Main Authors SHIPITSIN, MICHAIL, BLUME-JENSEN, PETER, MURSHID, AYESHA, MASSON, KRISTINA, WIGERUP, CAROLINE, DUNYAK, JAMES
Format Patent
LanguageChinese
English
Published 01.03.2024
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Provided herein are methods and systems for determining and/or validating response to a checkpoint kinase 1 (Chk1) inhibitor, a Wee1 inhibitor, an ATR inhibitor, or a combination thereof, and methods of administering a Chk1 inhibitor, a Wee1 inhibitor, an ATR inhibitor, or a combination thereof to a subject determined to be responsive to said therapy.
Bibliography:Application Number: TW202312126104